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Introduction and purpose: In last two decades elderly population of iran increased. Aim of present study was to review the lipid profile changes of elderly males in response to aerobic training and detraining.

Methods and Materials: In this semi-experimental study 22 elderly males of yasuj city ferdows nursing home selected and base on their aerobic power divided in two groups of experimental and control. Experimental group trained aerobic exercise 8 weeks, 3 session per week and 30- 45 minutes with intensity of 55- 75 percent of maximum heart rate per session and after that detrained 2 weeks. For evaluate lipid profile blood samples gathered in week 1, 8 and 10. For statistical analysis of data used K-S, repeated measure ANOVA and bonferroni post hoc tests (p≤0.05).

Findings: 8 weeks aerobic training significantly reduces LDL (p=0.003), VLDL (p=0.007), TG (p=0.007), Cho (p=0.003) and increased HDL (p=0.001) of elderly males, nevertheless 2 weeks detraining significantly increased LDL (p=0.001), VLDL (p=0.001), TG (p=0.002), Cholesterol (p=0.001) and decreased HDL (p=0.001) of elderly males.

Conclusion: Reduction of lipid profile following aerobic training and their increase with detraining, can represents this fact that useful and appropriate achievements of eight weeks aerobic training in elderlies who live in nursing home, will be destroyed by two weeks detraining.